Technology

Novel Genetic Editing Superpower in Squid Found According to Present Study


Scientists from the Marine Biological Laboratory or MBL of the University of Chicago, Massachusetts have discovered recently that the squid is capable of immensely editing its genetic instructions not just within its neurons' nucleus but also within the axon where neural projections send electrical impulses to its other neurons.


This discovery comes as a shock in the study of molecular biology according to the MBL as this challenges the vital belief and fundamental principle that genetic information is handed faithfully from the DNA to the messenger RNA and into the protein synthesis.


In 2015, Joshua Rosenthal and his colleagues have discovered that squids may edit or modify their messenger RNA instructions to an astonishing degree which allow them to improve what kinds of proteins will be released and produced in the nervous system,


This means that, theoretically, based on the results of the study , squids are capable of changing or modifying their protein function and tailor-fitting it to address the localized needs of the cell.


The team from MBL also showed that messenger RNAs which are modified in the axon of the nerve cells are edited at much higher and faster rates than in the organism's nucleus.


Previously, Rosenthal and his colleagues have shown that octopus and cuttlefish, cephalopod siblings of squids, also depend on mRNA editing to diversify the types of proteins that they can produce in the nervous system.






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