Luis Valbuena (left), who played 11 seasons in the majors, with the Los Angeles Angels, Houston Astros, Cleveland Indians and Seattle Mariners; and Jose Castillo, who played seven seasons in the MLB, including with the Pittsburgh Pirates.
The club tweeted, "We are living a horrible tragedy in Cardenales de Lara.
We lost our players Luis Valbuena and Jose Castillo in a traffic accident."
The newspaper cites media accounts as saying the person behind the wheel was the driver for former Arizona Diamondbacks player and winter ball teammate Carlos Rivero, 30.
He also had stints with the Seattle Mariners, Cleveland Indians, Chicago Cubs and Houston Astros.
Castillo was iln the majors from 2004 to 2008, with the Pittsburgh Pirates, San Francisco Giants and Astros.
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